Monday, January 18, 2010

Hepatitis B Vaccine

Infants and Children

Hepatitis B vaccination must be provide from children, because this virus is difficult being removed from human body. The supply of this vaccines for pediatric use adequate to meet the demand during 2009 in almost in all over the world.

 If the infants mother are confirmed to be HBsAg-negative, the infacts should receive a birth dose of monovalent hepatitis B vaccine and second dose of monovalent hepatitis B vaccine at 1-2 months of age. Monovalent hepatitis B vaccine should be used for doses administered before 6 weeks of age. These doses should not be delayed. A third dose of hepatitis B vaccine is recommended fro these infant at 6 – 18 months of age.

The birth dose of hepatitis B vaccines is a critical component of post exposure prophylaxis to prevent perinatal transmission of hepatitis B virus infection to infants from women who are HBs Ag-positive. Most infants and children who acquire hepatitis B infection before 5 years develop chronic hepatitis B infection, these infants and children have a 15% - 25% risk of liver cirrhosis and or heptocellular carcinoma.

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