Tuesday, April 6, 2010

New Vaccine Dosing Technology

The example of pathogen targeted:
Hepatitis B SAg, pertusis toxin surface protein A, CMV gB
Dengue Genes in yellow fever 17D, Para influenza 1 + 2 genes in Para influenza 3, M tuberculosis genes in BCG
HIV, CMV
HIV, Hemorhagic Fever
HPV, SARS
HIV and many others
HIV, malaria, tuberculosis
Meningococcus B
Mainly bacteria
Cancer, CTL vaccines
Hib
Influenza, parainfluenza, RSV

Starting from microbial DNA, cDNA or RNA
New Target groups for vaccination

Group
Vaccine Targets
Infants
(combination vaccines)
Diphtheria, tetanus, acellular pertusis, Hameophilus influenzae type b, hepatitis B, inactivated polio vaccine.
Adolescents
Tetanus, adult diphtheria dose, acellular pertussis, CMV, HPV, HSV-2
Adults
Zoster, HSV-2
Hospital patients
Staphlococcal, Candida
Pregnant women
Group B Streptococcus, RSV
Civil defence worker
New vaccinia, anthrax, plague, Ebola, etc.
Individual with non-infectious diseases
Cancer, Alzheimer disease, dental caries, autoimmune disorders, drug addiction.
Individual with chronic infections (therapeutic vaccines)
HIV, HPV

There are newer technology development use in dosing vaccines, this technology can use in several kind of vaccinations, the vaccine example that use this technology as follows:
  • Live Influenza
  • Measles
  • Rubella
  • Plants transgenic for Hepatitis BsAg
  • Hepatitis B, Anthrax

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